Gene: STAT4 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASDB Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis. 23053960 2012
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASDB We also found evidence for association (P < 1 x 10(-5)) at FCGR2A, PTPN22 and STAT4, regions previously associated with SLE and other autoimmune diseases, as well as at > or =9 other loci (P < 2 x 10(-7)). 18204446 2008
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASDB Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. 19165918 2008
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASDB Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. 21408207 2011
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASDB Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. 18204098 2008
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASDB Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. 23273568 2013
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASDB GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. 24871463 2014
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASDB Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193 2009
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 SusceptibilityMutation disease ORPHANET Genetics and epigenetics of systemic lupus erythematosus. 23943494 2013
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 SusceptibilityMutation disease ORPHANET Role of cytokines in systemic lupus erythematosus: recent progress from GWAS and sequencing. 22654485 2012
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 SusceptibilityMutation disease ORPHANET A SNP haplotype in the third intron of STAT4 was associated with susceptibility to both rheumatoid arthritis and systemic lupus erythematosus. 17804842 2007
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 Biomarker disease HPO
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease LHGDN The IFN regulatory factor 5 SLE risk genotype was associated with higher serum IFN-alpha activity; however, STAT4 showed dominant influence on the sensitivity of PBMC to serum IFN-alpha. 19109131 2009
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease LHGDN A SNP haplotype in the third intron of STAT4 was associated with susceptibility to both rheumatoid arthritis and systemic lupus erythematosus. 17804842 2007
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease LHGDN The risk allele of the SNP rs7582694 in STAT4 correlated to production of anti-dsDNA (double-stranded DNA) antibodies and displayed a multiplicatively increased, 1.82-fold risk of SLE with two independent risk alleles of the IRF5 (interferon regulatory factor 5) gene. 18579578 2008
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease LHGDN We confirmed that four SNPs in very high LD (r(2) = 0.94 to 0.99) were most strongly associated with SLE, and there was no compelling evidence for additional SLE risk loci in the STAT4 region. 18516230 2008
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASCAT Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. 18204098 2008
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASCAT Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases. 30573655 2019
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASCAT Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. 19165918 2008
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASCAT Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193 2009
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASCAT Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus. 27399966 2016
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASCAT Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans. 26663301 2016
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASCAT Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. 21408207 2011
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASCAT Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. 26502338 2015
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.700 GeneticVariation disease GWASCAT Transancestral mapping and genetic load in systemic lupus erythematosus. 28714469 2017